Evaluating the Efficacy of AVAPS versus BiPAP in Managing COPD Exacerbations

Author: Tariq Cheema, MD, FCCP, MMM

Abstract: This project aims to evaluate the effectiveness of Average Volume Assured Pressure Support (AVAPS) versus Bi-level Positive Airway Pressure (BiPAP) in managing Chronic Obstructive Pulmonary Disease (COPD) exacerbations. Chronic Obstructive Pulmonary Disease is a significant global health issue, with high morbidity, healthcare utilization, and associated costs. Non-invasive ventilation (NIV) strategies like AVAPS and BiPAP have shown promise in reducing mortality, intubation rates, hospital stay durations, and complications. This study will prospectively compare these modalities in a real-world setting to determine their impact on patient-reported outcomes, adherence rates, hospital readmission rates, and gas exchange metrics. The research will involve a comprehensive multidisciplinary team and a detailed methodology incorporating randomization, monitoring, and evaluation of key metrics. The expected outcomes include identifying the most effective NIV device for managing and preventing COPD exacerbations, thereby enhancing patient care and outcomes. This study’s findings could significantly influence clinical practice, offering evidence-based guidance on the optimal NIV strategy, improving patient outcomes, and reducing healthcare costs.